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doi:10.3109/13590849208997961

The remaining ROS is produced by lipoxygenases and the Fenton reaction (Zhang et al., 2025a)

Extensive research has established glutathione peroxidase 4 (GPX4) as a critical regulator in the pathogenesis of multiple pathological conditions, including osteoarthritis 35 ,cancers 47 , and liver disease 48